Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19012762 | 0.90 | LMNA (0.47) | OPRM1DRD4MAPTCHRM4CHRM2 | |
| SCHEMBL19012635 | 0.89 | KDM4E (0.49) | OPRM1DRD4MAPTCHRM4CHRM2 | |
| SCHEMBL19001026 | 0.86 | OPRM1 (0.41) | OPRM1MAPTCHRM2 | |
| SCHEMBL24575714 | 0.83 | OPRM1 (0.44) | OPRM1DRD4MAPTCHRM4CHRM2 | |
| SCHEMBL24575713 | 0.83 | OPRM1 (0.44) | OPRM1DRD4MAPTCHRM4CHRM2 | |
| SCHEMBL25154429 | 0.83 | OPRM1 (0.44) | OPRM1DRD4MAPTCHRM4CHRM2 | |
| SCHEMBL25154524 | 0.83 | OPRM1 (0.44) | OPRM1DRD4MAPTCHRM4CHRM2 | |
| SCHEMBL21336571 | 0.81 | CHRNA7 (0.48) | OPRM1MAPTBPTFSIGMAR1 | |
| SCHEMBL3165425 | 0.81 | MC4R (0.48) | MAPTCHRM4CHRM2CHRM5ACHE | |
| SCHEMBL3165429 | 0.81 | MC4R (0.48) | MAPTCHRM4CHRM2CHRM5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |