Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22781213 | 0.81 | RORC (0.44) | NR1H2NR1H3RORCMEN1KMT2A | |
| SCHEMBL18448053 | 0.81 | RORC (0.44) | NR1H2NR1H3RORCMEN1KMT2A | |
| SCHEMBL20757654 | 0.78 | PDE4B (0.48) | DPP4PDE4BRORCHRH3USP30 | |
| SCHEMBL16640402 | 0.76 | DPP4 (0.43) | ADAMTS5MMP2MMP13MMP14DPP4 | |
| SCHEMBL6956458 | 0.74 | MGLL (0.40) | — | |
| SCHEMBL18640901 | 0.73 | DPP4 (0.37) | ADAMTS5MMP2MMP13MMP14NR1H2 | |
| SCHEMBL19271005 | 0.72 | PDE4B (0.51) | ADAMTS5DPP4PDE4BPDE4APDE4C | |
| SCHEMBL19270998 | 0.72 | PDE4B (0.50) | ADAMTS5MMP2MMP13MMP14DPP4 | |
| SCHEMBL5160786 | 0.71 | DDB1 (0.46) | ADAMTS5MMP2MMP13MMP14NR1H2 | |
| SCHEMBL19702757 | 0.71 | DPP4 (0.55) | DPP4PDE4BDDB1CRBNHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137512-B | Cyclic N-amide compounds useful as herbicides | FMC公司 | 2022-05-31 | — | — | CN | disclosed |
| US-11178873-B2 | Cyclic N-carboxamide compounds useful as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| EP-3328836-B1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORP (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10653148-B2 | — | — | 2020-05-19 | — | — | US | disclosed |
| US-20180213788-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | FMC CORPORATION | 2018-08-02 | — | — | US | disclosed |
| CN-108137512-A | Cyclic n nitroso compound-amide compound as herbicide | 杜邦公司 | 2018-06-08 | — | — | CN | disclosed |
| EP-3328836-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017023515-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10653148-B2 | — | CYP1B1, CYP1A1, C5 | ADAMTS5 3387/4885MMP2 2635/4885MMP13 2904/4885 |
| US-11178873-B2 | Cyclic N-carboxamide compounds useful as herbicides | CHRM2, NIT2, CHRM1 | ADAMTS5 4567/4885MMP2 3658/4885MMP13 4373/4885 |
| US-20180213788-A1 | CYCLIC N-CARBOXAMIDE COMPOUNDS USEFUL AS HERBICIDES | CHRM2, NIT2, CHRM1 | ADAMTS5 4567/4885MMP2 3658/4885MMP13 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.