Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15684448 | 0.84 | — | — | |
| SCHEMBL82090 | 0.81 | — | — | |
| SCHEMBL27289177 | 0.81 | TDP1 (0.43) | TDP1SLC6A4SLC6A2HTR3AKCNH2 | |
| SCHEMBL3492200 | 0.79 | CTSL (0.31) | — | |
| Hydrochloric Acid SCHEMBL796439 | 0.79 | TDP1 (0.53) | TDP1SLC6A4SLC6A2HTR3AKCNH2 | |
| SCHEMBL7518042 | 0.79 | TDP1 (0.42) | TDP1SLC6A4SLC6A2HTR3AKCNH2 | |
| SCHEMBL16394631 | 0.79 | TDP1 (0.42) | TDP1SLC6A4SLC6A2HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL27035712 | 0.79 | TDP1 (0.47) | TDP1SLC6A4SLC6A2HTR3AKCNH2 | |
| SCHEMBL91544 | 0.77 | TDP1 (0.43) | TDP1SLC6A4SLC6A2HTR3AKCNH2 | |
| SCHEMBL13697527 | 0.77 | CYP1A2 (0.34) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676727-B2 | Myxovirus therapeutics, compounds, and uses related thereto | EMORY UNIVERSITY (US) | 2017-06-13 | — | — | US | disclosed |
| EP-2771324-B1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | UNIV EMORY (US) | 2017-02-01 | — | — | EP | disclosed |