SCHEMBL3492200

SCHEMBL3492200

COCOCC1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSK P43235 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13697527 0.98 CYP1A2 (0.34) CTSLCTSBCTSKLMNACYP1A2
SCHEMBL15684448 0.90
SCHEMBL14598913 0.85 ALDH1A1 (0.32)
SCHEMBL23383095 0.82 CTSL (0.33) CTSLCTSBCTSK
SCHEMBL14338963 0.81 CTSL (0.39) CTSLCTSBCTSKLMNACYP1A2
SCHEMBL18455136 0.79 TDP1 (0.44)
SCHEMBL19749310 0.79 SHBG (0.31)
SCHEMBL6177197 0.78 SLC1A3 (0.33) CTSLCTSBCTSKLMNA
SCHEMBL87257 0.78
SCHEMBL22454265 0.78 CTSL (0.31) CTSLCTSBCTSKLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170305848-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2017-10-26 US disclosed
US-20170305848-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2017-10-26 US disclosed
EP-3199520-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION Tokyo Ohka Kogyo Co., Ltd. (JP) 2017-08-02 EP disclosed
US-8759362-B2 Bicycloheteroaryl compounds and their use as TRPV1 ligands PURDUE PHARMA L.P. (US) 2014-06-24 US disclosed
US-8703962-B2 Monocyclic compounds and their use as TRPV1 ligands PURDUE PHARMA L.P. (US) 2014-04-22 US disclosed
US-8546388-B2 Heterocyclic TRPV1 receptor ligands PURDUE PHARMA L.P. (US) 2013-10-01 US disclosed
US-20100137306-A1 HETEROCYCLIC TRPV1 RECEPTOR LIGANDS PURDUE PHARMA L.P. 2010-06-03 US disclosed
US-20100130499-A1 BICYCLOHETEROARYL COMPOUNDS AND THEIR USE AS TRPV1 LIGANDS PURDUE PHARMA L.P. 2010-05-27 US disclosed
US-20100120862-A1 MONOCYCLIC COMPOUNDS AND THEIR USE AS TRPV1 LIGANDS PURDUE PHARMA L.P. 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130499-A1 BICYCLOHETEROARYL COMPOUNDS AND THEIR USE AS TRPV1 LIGANDS TRPV1, TRPA1, TRPV3 CTSL 2260/4885CTSB 1507/4885CTSK 903/4885
US-20170305848-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION ARSA, SPIN1, ASIC1 CTSL 3449/4885CTSB 3526/4885CTSK 2737/4885
US-20100137306-A1 HETEROCYCLIC TRPV1 RECEPTOR LIGANDS TRPV1, TRPA1, TRPV2 CTSL 3991/4885CTSB 2590/4885CTSK 2495/4885
US-20100120862-A1 MONOCYCLIC COMPOUNDS AND THEIR USE AS TRPV1 LIGANDS TRPV1, TRPA1, TRPV2 CTSL 3023/4885CTSB 1863/4885CTSK 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.