Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19497042 | 0.82 | BTK (0.64) | BTKLCKSRC | |
| SCHEMBL18455445 | 0.81 | BTK (0.47) | BTKLCKSRC | |
| SCHEMBL18455260 | 0.78 | BTK (0.64) | BTKLCKSRC | |
| SCHEMBL18455257 | 0.78 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL19497175 | 0.78 | BTK (0.54) | BTK | |
| SCHEMBL18455658 | 0.78 | BTK (0.74) | BTKLCKSRC | |
| SCHEMBL18455263 | 0.77 | BTK (0.49) | BTK | |
| SCHEMBL18455441 | 0.77 | BTK (0.49) | BTK | |
| SCHEMBL18455270 | 0.74 | BTK (0.55) | BTK | |
| SCHEMBL23638956 | 0.73 | BTK (1.00) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970202-B1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICALS CO (JP) | 2017-02-01 | — | — | EP | disclosed |