Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18455263 | 0.84 | BTK (0.49) | BTKPARP1 | |
| SCHEMBL18455270 | 0.81 | BTK (0.55) | BTKGAAPARP1 | |
| SCHEMBL18455239 | 0.77 | BTK (0.64) | BTK | |
| SCHEMBL19497175 | 0.74 | BTK (0.54) | BTK | |
| SCHEMBL19497121 | 0.72 | BTK (0.54) | BTK | |
| SCHEMBL16008906 | 0.72 | BTK (0.45) | BTKCHEK1 | |
| SCHEMBL16008905 | 0.72 | BTK (0.45) | BTKCHEK1 | |
| SCHEMBL16016639 | 0.72 | BTK (0.43) | BTKCHEK1 | |
| Hydrochloric Acid SCHEMBL16008488 | 0.71 | BTK (0.44) | BTKCHEK1 | |
| Hydrochloric Acid SCHEMBL16009014 | 0.71 | BTK (0.42) | BTKCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235814-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2017-10-25 | — | — | EP | disclosed |
| EP-2970202-B1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICALS CO (JP) | 2017-02-01 | — | — | EP | disclosed |