Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 12/20 | 0.59 |
| ▸ | SCN2B | O60939 | 3/20 | 0.52 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680487 | 0.84 | SCN9A (0.59) | SCN9ASCN5A | |
| SCHEMBL18455369 | 0.83 | P4HTM (0.52) | SCN9ASCN5ANPC1RAB9AP4HTM | |
| SCHEMBL20418633 | 0.82 | HDAC6 (0.62) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16618358 | 0.82 | SCN9A (0.57) | SCN9ASCN2BSCN1BSCN5AP4HTM | |
| SCHEMBL20370959 | 0.80 | SCN9A (0.55) | SCN9ASCN2BSCN1BSCN5AP4HTM | |
| SCHEMBL8918916 | 0.79 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL680061 | 0.78 | SCN9A (0.55) | SCN9ASCN2BSCN1BSCN5ASCN1A | |
| SCHEMBL29225419 | 0.77 | ALDH1A1 (0.55) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7990845 | 0.77 | FLT1 (0.65) | SCN9ASCN2BSCN1BSCN5AP4HTM | |
| SCHEMBL22097497 | 0.77 | P4HTM (0.49) | SCN9ASCN2BSCN1BSCN5ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017017607-A1 | BETUIN DERIVATIVES FOR PREVENTING OR TREATING HIV INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-02-02 | — | — | WO | disclosed |