Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 6/20 | 0.65 |
| ▸ | FLT4 | P35916 | 6/20 | 0.65 |
| ▸ | KDR | P35968 | 6/20 | 0.65 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | SCN2B | O60939 | 1/20 | 0.55 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319859 | 0.90 | MMP1 (0.56) | FLT1FLT4KDRSCN9AMAP4K4 | |
| SCHEMBL366081 | 0.82 | MAOA (0.63) | SCN9ASCN5AALDH1A1MAPTMAOA | |
| SCHEMBL365210 | 0.82 | MAOA (0.63) | SCN9ASCN5AALDH1A1MAPTMAOA | |
| SCHEMBL10701740 | 0.82 | FLT1 (0.67) | FLT1FLT4KDRL3MBTL1KDM4E | |
| SCHEMBL279954 | 0.82 | HDAC1 (0.63) | SCN9AALDH1A1LMNAP4HTMPTGS2 | |
| SCHEMBL7984827 | 0.81 | FLT1 (0.61) | FLT1FLT4KDRL3MBTL1KDM4E | |
| SCHEMBL17971206 | 0.81 | KDM4E (0.62) | SCN9ASCN5AKDM4ELMNAP4HTM | |
| SCHEMBL10339331 | 0.81 | MAOA (0.57) | FLT1FLT4KDRL3MBTL1KDM4E | |
| SCHEMBL1647742 | 0.80 | LMNA (0.54) | SCN9AMAP4K4L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL10702289 | 0.80 | FLT1 (0.65) | FLT1FLT4KDRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |