Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21705280 | 0.79 | HDAC3 (0.38) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7792783 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28348235 | 0.77 | ALDH1A1 (0.71) | ALDH1A1FAAHCNR1CNR2KDM4E | |
| SCHEMBL31140049 | 0.76 | ALDH1A1 (0.89) | ALDH1A1FAAHCNR1CNR2KDM4E | |
| SCHEMBL1930571 | 0.76 | ALDH1A1 (0.89) | ALDH1A1FAAHCNR1CNR2KDM4E | |
| SCHEMBL9069200 | 0.76 | ALDH1A1 (0.89) | ALDH1A1FAAHCNR1CNR2KDM4E | |
| SCHEMBL1702480 | 0.76 | ALDH1A1 (0.89) | ALDH1A1FAAHCNR1CNR2KDM4E | |
| SCHEMBL29723317 | 0.76 | ALDH1A1 (0.89) | ALDH1A1FAAHCNR1CNR2KDM4E | |
| SCHEMBL21333932 | 0.76 | ALDH1A1 (0.89) | ALDH1A1FAAHCNR1CNR2KDM4E | |
| SCHEMBL6725121 | 0.75 | ESR1 (0.58) | ALDH1A1FAAHCNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484585-A | CONTAIN NONIONIC, CATIONIC, ANIONIC, ZWITTERIONIC SURFACTANTS, EXCIPIENTS, AND WATER; X-RAY CONTRAST AND COMPUTED TOMOGRAPHY; MEDICAL DIAGNOSIS | STERLING-WINTHROP INC. (US) | 1996-01-16 | — | — | US | claimed |
| US-5385720-A | X-ray radiology and computer tomography; uniform coating of the soft tissues; medical diagnosis | STERLING WINTHROP INC. (US) | 1995-01-31 | — | — | US | claimed |
| EP-0614669-A2 | Compositions of iodobenzoic acid derivatives in filmforming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-09-14 | — | — | EP | claimed |
| EP-0614668-A2 | Composition of iodobenzoic acid derivatives for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-09-14 | — | — | EP | claimed |
| US-5344638-A | Contrast agents for medicine | STERLING WINTHROP INC. (US) | 1994-09-06 | — | — | US | claimed |
| US-5312616-A | Radiopaque coating for x-ray examination | STERLING WINTHROP INC. (US) | 1994-05-17 | — | — | US | claimed |
| JP-6321867-A | — | — | None | — | — | JP | disclosed |
| US-9718929-B2 | Chelating amphiphilic polymers | KONINKLIJKE PHILIPS N.V. (NL) | 2017-08-01 | — | — | US | disclosed |
| US-20150247008-A1 | CHELATING AMPHIPHILIC POLYMERS | KONINKL PHILIPS NV (NL) | 2015-09-03 | — | — | US | disclosed |
| EP-2323636-B1 | CHELATING AMPHIPHILIC POLYMERS | KONINKL PHILIPS NV (NL) | 2015-08-12 | — | — | EP | disclosed |
| US-9034298-B2 | Chelating amphiphilic polymers | KONINKLIJKE PHILIPS N.V. (NL) | 2015-05-19 | — | — | US | disclosed |
| US-8846035-B2 | Methods for preparing polymer microparticles | KONINKLIJKE PHILIPS N.V. (NL) | 2014-09-30 | — | — | US | disclosed |
| US-8313676-B2 | Methods for preparing polymer microparticles | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-20 | — | — | US | disclosed |
| US-5484585-A | CONTAIN NONIONIC, CATIONIC, ANIONIC, ZWITTERIONIC SURFACTANTS, EXCIPIENTS, AND WATER; X-RAY CONTRAST AND COMPUTED TOMOGRAPHY; MEDICAL DIAGNOSIS | STERLING-WINTHROP INC. (US) | 1996-01-16 | — | — | US | disclosed |
| WO-1995028969-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING PHARMACEUTICALLY ACCEPTABLE CLAYS | NYCOMED IMAGING AS (NO) | 1995-11-02 | — | — | WO | disclosed |
| JP-H06321867-A | X-RAY CONTRAST AGENT AND X-RAY CONTRAST AGENT COMPOSITION | STERLING WINTHROP INC | 1994-11-22 | — | — | JP | disclosed |
| EP-0614669-A2 | Compositions of iodobenzoic acid derivatives in filmforming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-09-14 | — | — | EP | disclosed |
| EP-0614668-A2 | Composition of iodobenzoic acid derivatives for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-09-14 | — | — | EP | disclosed |
| US-5344638-A | Contrast agents for medicine | STERLING WINTHROP INC. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5312616-A | Radiopaque coating for x-ray examination | STERLING WINTHROP INC. (US) | 1994-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150247008-A1 | CHELATING AMPHIPHILIC POLYMERS | SLC30A5, SLC30A6, ABCB4 | ALDH1A1 4768/4885FAAH 1047/4885CNR1 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.