SCHEMBL184582

SCHEMBL184582

C=CC(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.45
USP2 O75604 1/20 0.45
MAPT P10636 1/20 0.45
ALDH1A1 P00352 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710565 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL2032533 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL1263585 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL1263587 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL10591032 0.98 TSHR (0.44) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL1263184 0.98 ALDH1A1 (0.44) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL37167 0.93 ALDH1A1 (0.46) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL30927588 0.88 USP2 (0.38) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL31453082 0.88 TSHR (0.38) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL12703438 0.88 ALDH1A1 (0.53) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186731-B2 Slippery self-lubricating polymer surfaces PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-11-30 US claimed
US-10584278-B2 Proppant having amphiphobic coatings and methods for making and using same CARBO CERAMICS INC. (US) 2020-03-10 US claimed
US-20190225878-A1 PROPPANT HAVING AMPHIPHOBIC COATINGS AND METHODS FOR MAKING AND USING SAME CARBO CERAMICS INC. 2019-07-25 US claimed
US-10246632-B2 Proppant having amphiphobic coatings and methods for making and using same CARBO CERAMICS INC. (US) 2019-04-02 US claimed
US-20180327608-A1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-11-15 US claimed
US-20170121596-A1 PROPPANT HAVING AMPHIPHOBIC COATINGS AND METHODS FOR MAKING AND USING SAME CARBO CERAMICS, INC. 2017-05-04 US claimed
EP-2401309-B1 ELECTRICALLY ISOLATING POLYMER COMPOSITION CORNING INC (US) 2015-06-17 EP claimed
US-20120037400-A1 ELECTRICALLY ISOLATING POLYMER COMPOSITION FIELDS LENWOOD L (US) 2012-02-16 US claimed
EP-2401309-A2 ELECTRICALLY ISOLATING POLYMER COMPOSITION Corning Inc. (US) 2012-01-04 EP claimed
WO-2010099254-A2 ELECTRICALLY ISOLATING POLYMER COMPOSITION CORNING INCORPORATED (US) 2010-09-02 WO claimed
US-20100215968-A1 ELECTRICALLY ISOLATING POLYMER COMPOSITION CORNING INCORPORATED 2010-08-26 US claimed
EP-3688046-B1 COPOLYMERS OF HALOGENATED OLEFINS AND HALOGENATED CO-MONOMERS ARKEMA INC (US) 2026-01-07 EP disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
WO-2025043220-A1 FLUID CONDUITS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-02-27 WO disclosed
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
WO-1993023773-A1 PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL CIBA-GEIGY AG (CH) 1993-11-25 WO disclosed
US-5235013-A Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester CIBA-GEIGY CORPORATION 1993-08-10 US disclosed
US-5032641-A Acrylic ester polymers, silicon-containing addition polymer KANSAI PAINT CO., LTD. (JP) 1991-07-16 US disclosed
EP-0348946-A1 Water-repellent film-forming composition KANSAI PAINT CO., LTD. (JP) 1990-01-03 EP disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed