SCHEMBL710565

SCHEMBL710565

C=CC(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.45
USP2 O75604 1/20 0.45
MAPT P10636 1/20 0.45
ALDH1A1 P00352 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2032533 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL1263585 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL184582 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL1263587 1.00 TSHR (0.45) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL10591032 0.98 TSHR (0.44) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL1263184 0.98 ALDH1A1 (0.44) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL37167 0.93 ALDH1A1 (0.46) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL30927588 0.88 USP2 (0.38) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL31453082 0.88 TSHR (0.38) TSHRUSP2MAPTALDH1A1TP53
SCHEMBL12703438 0.88 ALDH1A1 (0.53) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 706 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3573461-B1 ANTIMICROBIAL, NON-THROMBOGENIC POLYMER COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2026-04-22 EP claimed
US-20250357551-A1 AQUEOUS ELECTROLYTE COMPOSITION AND AQUEOUS SECONDARY BATTERY COMPRISING SAME DAEGU GYEONGBUK INST SCIENCE & TECH (KR) 2025-11-20 US claimed
US-12476274-B2 Polymeric-inorganic hybrid layer for a lithium anode Lyten, Inc. (US) 2025-11-18 US claimed
US-20250328075-A1 PHOTOCURABLE COMPOSITION FOR FORMING AN IMPRINT LITHOGRAPHY TEMPLATE CANON KK (JP) 2025-10-23 US claimed
US-12444749-B2 Anode protective layer for lithium-sulfur cylindrical cells Lyten, Inc. (US) 2025-10-14 US claimed
CN-119403564-A Use of microbiota modulators for enhancing bone development and/or bone strength 雀巢产品有限公司 2025-02-07 CN claimed
US-20250004199-A1 LOW REFRACTIVE INDEX RESIN COMPOSITION FOR TPP NANO 3D PRINTING AND PHOTONIC WIRE BONDING METHOD USING THE SAME LUVANTIX ADM., CO. LTD (KR) 2025-01-02 US claimed
US-20240429448-A1 Silicon-Based Energy Storage Devices With Carboxylic Ether, Carboxylic Acid Based Salt, or Acrylate Electrolyte Containing Electrolyte Additives ENEVATE CORP (US) 2024-12-26 US claimed
US-20240384131-A1 MULTIFUNCTIONAL MODIFIED SILANE COMPOUND AND MANUFACTURE METHOD THEREOF, HARDENED COATING LAYER AND MANUFACTURE METHOD THEREOF SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-11-21 US claimed
US-12126024-B2 Battery including multiple protective layers Lyten, Inc. (US) 2024-10-22 US claimed
WO-2008149134-A2 ANTIFOULING COMPOSITION SI LABORATORIES LIMITED (GB) 2008-12-11 WO claimed
US-20080143003-A1 Actinically curable silicone hydrogel copolymers and uses thereof ALCON INC. (CH) 2008-06-19 US claimed
US-6870662-B2 Methods of surface modification for improving electrophoretic display performance SIPIX IMAGING, INC. (US) 2005-03-22 US claimed
EP-0449274-B1 Fluoroacrylic polymer having lubricating effect and thermoplastic resin composition comprising same MITSUBISHI RAYON CO (JP) 1995-10-04 EP claimed
US-5288825-A Fluoroalkyl acrylate or methacrylate copolymer; stain resistance, lubricants MITSUBISHI RAYON COMPANY LTD. (JP) 1994-02-22 US claimed
EP-0449274-A1 Fluoroacrylic polymer having lubricating effect and thermoplastic resin composition comprising same MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-10-02 EP claimed
US-4737556-A CROSSLINKED COPOLYMERS OF FLUOROALKYL ACRYLIC ESTERS; UNNECESSARY TO STERILIZE BY BOILING; ANTISOILANTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-04-12 US claimed
US-4387203-A COPOLYMER OF AN UNSATURATED NITRILE, CONJUGATED DIENE AND UNSATURATED FLUORINE COMPOUND GASOLINE RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-06-07 US claimed
US-4023995-A AMMONIUM PERCHLORATE, FLUOROALKYL ACRYLATE THIOKOL CORPORATION (US) 1977-05-17 US claimed
US-3983816-A COMPOSITIONS FOR PRODUCING FLICKERING SIGNALS THIOKOL CORPORATION (US) 1976-10-05 US claimed