SCHEMBL18458451

SCHEMBL18458451

Cc1scc(-c2ccccc2)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.48
CYP2B6 P20813 1/20 0.48
HPGD P15428 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 4/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
HTT P42858 1/20 0.40
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PRKCZ Q05513 1/20 0.39
GRM5 P41594 1/20 0.38
CYP17A1 P05093 2/20 0.37
CYP1A2 P05177 2/20 0.37
DAPK3 O43293 1/20 0.37
PRKD3 O94806 1/20 0.37
MAP4K4 O95819 1/20 0.37
ABL1 P00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27836567 0.80 CYP2A6 (0.47) CYP2A6CYP2B6HPGDALDH1A1LMNA
SCHEMBL13093611 0.77 CYP2A6 (0.57) CYP2A6CYP2B6ALDH1A1CYP17A1CYP1A2
SCHEMBL31526404 0.75 PDCD1 (0.43) CYP2A6CYP2B6HPGDSMN1; SMN2ALDH1A1
SCHEMBL6277246 0.74 GPR35 (0.49) CYP2A6CYP2B6HPGDSMN1; SMN2ALDH1A1
SCHEMBL13712822 0.74 KMT2A (0.52) HPGDSMN1; SMN2ALDH1A1LMNAPOLB
SCHEMBL11948739 0.74 ALDH1A1 (0.49) CYP2A6CYP2B6HPGDSMN1; SMN2ALDH1A1
SCHEMBL26038505 0.72 KMT2A (0.50) CYP2A6CYP2B6HPGDSMN1; SMN2ALDH1A1
SCHEMBL4760304 0.72 CA1 (0.42) CYP2A6CYP2B6HPGDALDH1A1LMNA
SCHEMBL28461110 0.71 CYP2A6 (0.43) CYP2A6CYP2B6HPGDSMN1; SMN2ALDH1A1
SCHEMBL15391338 0.70 PDPK1 (0.47) CYP2A6CYP2B6HPGDSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017018617-A1 NOVEL COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME, AND COLOR FILTER 삼성에스디아이 주식회사 2017-02-02 WO disclosed