SCHEMBL18458741

SCHEMBL18458741

CCC(N)C1CCC(C2CCC(c3ccc(F)cc3)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 18/20 0.40
DPP9 Q86TI2 15/20 0.40
DPP8 Q6V1X1 12/20 0.40
DPP7 Q9UHL4 12/20 0.40
KDM1A O60341 1/20 0.36
RCOR1 Q9UKL0 1/20 0.36
SPHK1 Q9NYA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458913 0.91 DPP4 (0.40) DPP4DPP9DPP8DPP7KDM1A
SCHEMBL19619424 0.86 SPHK1 (0.47) DPP4DPP9DPP8DPP7KDM1A
SCHEMBL18458889 0.86 SLC18A3 (0.34) SPHK1
SCHEMBL18800271 0.86 SLC18A3 (0.34) DPP4DPP9DPP8DPP7SPHK1
SCHEMBL20929628 0.85 SPHK1 (0.39) SPHK1
SCHEMBL18458906 0.85 DRD2 (0.45) KDM1ARCOR1
SCHEMBL18458837 0.84 DPP4 (0.40) DPP4DPP9DPP8DPP7
SCHEMBL20160836 0.84 DPP4 (0.40) DPP4DPP9DPP8DPP7
SCHEMBL18458722 0.84 DPP4 (0.36) DPP4DPP9DPP8DPP7
SCHEMBL20280564 0.83 DPP4 (0.37) DPP4DPP9DPP8DPP7KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 US disclosed
US-10208250-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-02-19 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-20170260451-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-09-14 US disclosed
US-9695361-B2 Liquid crystal composition and liquid crystal display element using the same DIC CORPORATION (JP) 2017-07-04 US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 US disclosed
US-9624434-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-04-18 US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 US disclosed