Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458501 | 0.91 | SPHK1 (0.39) | SPHK1CYP2C9SPHK2GRIA1GRIA2 | |
| SCHEMBL20280445 | 0.87 | GRIA1 (0.38) | SPHK1GRIA1GRIA2GRIA3ALDH1A1 | |
| SCHEMBL18800271 | 0.86 | SLC18A3 (0.34) | SPHK1CYP2C9GRIA1GRIA2GRIA3 | |
| SCHEMBL18458889 | 0.86 | SLC18A3 (0.34) | SPHK1CYP2C9ALDH1A1MAPTMEN1 | |
| SCHEMBL19619424 | 0.86 | SPHK1 (0.47) | SPHK1CYP2C9GRIA1GRIA2GRIA3 | |
| SCHEMBL18458741 | 0.85 | DPP4 (0.40) | SPHK1 | |
| SCHEMBL18458906 | 0.85 | DRD2 (0.45) | CYP2C9MAPTMEN1KMT2ALMNA | |
| SCHEMBL19415926 | 0.83 | SPHK1 (0.36) | SPHK1CYP2C9SPHK2 | |
| SCHEMBL18458707 | 0.82 | DRD2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL18458611 | 0.81 | KDM1A (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119573-A1 | COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | DIC CORPORATION (JP) | 2019-04-25 | — | — | US | disclosed |