SCHEMBL18459809

SCHEMBL18459809

NC1CCC(S(=O)(=O)O)C1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
GABRA1 P14867 1/20 0.41
TSHR P16473 1/20 0.41
GABRG2 P18507 1/20 0.41
NFKB1 P19838 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRA6 Q16445 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6369437 0.86 LMNA (0.38) LMNACYP3A4GABRA1TSHRGABRG2
SCHEMBL8772810 0.84 TSHR (0.50) LMNACYP3A4GABRA1TSHRGABRG2
SCHEMBL11801018 0.82 LMNA (0.48) LMNACYP3A4GABRA1TSHRGABRG2
SCHEMBL28382980 0.81
SCHEMBL28382979 0.81
SCHEMBL11096793 0.81 TSHR (0.50) LMNACYP3A4GABRA1TSHRGABRG2
SCHEMBL23548930 0.77 APLNR (0.37)
SCHEMBL26117541 0.77 APLNR (0.37)
SCHEMBL26113103 0.77 APLNR (0.37)
SCHEMBL26110454 0.77 APLNR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12187668-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2025-01-07 US disclosed
EP-3334710-B1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2023-10-04 EP disclosed
EP-3334710-B1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2023-10-04 EP disclosed
EP-4209130-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF DSM Nutritional Products, LLC (US) 2023-07-12 EP disclosed
EP-4205553-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF DSM Nutritional Products, LLC (US) 2023-07-05 EP disclosed
US-20230133465-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2023-05-04 US disclosed
US-20230133465-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2023-05-04 US disclosed
CN-108026049-B Compositions and methods for treating and preventing neurodegenerative disorders 阿尔泽恩股份有限公司 2021-08-31 CN disclosed
US-11053192-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2021-07-06 US disclosed
US-11053192-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2021-07-06 US disclosed
US-20200347012-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2020-11-05 US disclosed
US-20200347012-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2020-11-05 US disclosed
US-10590070-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2020-03-17 US disclosed
US-10590070-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2020-03-17 US disclosed
EP-3459975-A1 POLYMERIC ACID CATALYSTS AND USES THEREOF Cadena Bio, Inc. (US) 2019-03-27 EP disclosed
EP-3334710-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS Alzheon, Inc. (US) 2018-06-20 EP disclosed
CN-108026049-A COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS 阿尔泽恩股份有限公司 2018-05-11 CN disclosed
EP-2681247-B1 Polymers containing an acid group and their use as a catalyst CADENA BIO INC (US) 2018-04-04 EP disclosed
WO-2017027582-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. (US) 2017-02-16 WO disclosed
WO-2016122887-A9 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2017-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133465-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS PSEN2, CLN6, PSEN1 LMNA 160/4885CYP3A4 4603/4885GABRA1 2674/4885
US-11053192-B2 Compositions and methods for treating and preventing neurodegenerative disorders PSEN2, CLN6, PSEN1 LMNA 160/4885CYP3A4 4603/4885GABRA1 2674/4885
US-12187668-B2 Compositions and methods for treating and preventing neurodegenerative disorders PSEN2, CLN6, PSEN1 LMNA 160/4885CYP3A4 4603/4885GABRA1 2674/4885
US-10590070-B2 Compositions and methods for treating and preventing neurodegenerative disorders PSEN2, CLN6, PSEN1 LMNA 160/4885CYP3A4 4603/4885GABRA1 2674/4885
US-20200347012-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS PSEN2, CLN6, PSEN1 LMNA 160/4885CYP3A4 4603/4885GABRA1 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.