Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.38 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18463521 | 0.91 | PDK2 (0.38) | PDK2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL18463561 | 0.90 | L3MBTL1 (0.41) | PDK2SMN1; SMN2L3MBTL1NFKB1NFKB2 | |
| SCHEMBL18463295 | 0.90 | L3MBTL1 (0.41) | PDK2SMN1; SMN2L3MBTL1NFKB1NFKB2 | |
| SCHEMBL22059018 | 0.90 | L3MBTL1 (0.41) | PDK2SMN1; SMN2L3MBTL1NFKB1NFKB2 | |
| SCHEMBL17252444 | 0.89 | L3MBTL1 (0.43) | PDK2SMN1; SMN2L3MBTL1NFKB1NFKB2 | |
| SCHEMBL19271443 | 0.88 | SMN1; SMN2 (0.36) | PDK2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL13314078 | 0.87 | PDK2 (0.41) | PDK2PGRMAPK1TSHR | |
| SCHEMBL25774938 | 0.87 | L3MBTL1 (0.54) | PDK2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26444848 | 0.86 | L3MBTL1 (0.39) | PDK2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL20465232 | 0.86 | PDK2 (0.37) | PDK2NPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222872-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| WO-2017016630-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222872-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, NES, PIR | PDK2 364/4885NPC1 3504/4885RAB9A 2955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.