Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18467491 | 1.00 | L3MBTL1 (0.33) | L3MBTL1SMYD3ALDH1A1TRPM8 | |
| SCHEMBL14950801 | 1.00 | L3MBTL1 (0.33) | L3MBTL1SMYD3ALDH1A1TRPM8 | |
| SCHEMBL18467490 | 1.00 | L3MBTL1 (0.33) | L3MBTL1SMYD3ALDH1A1TRPM8 | |
| SCHEMBL14950802 | 1.00 | L3MBTL1 (0.33) | L3MBTL1SMYD3ALDH1A1TRPM8 | |
| SCHEMBL12139932 | 0.85 | TRPM8 (0.34) | L3MBTL1SMYD3ALDH1A1TRPM8 | |
| SCHEMBL10210966 | 0.85 | TRPM8 (0.34) | L3MBTL1SMYD3ALDH1A1TRPM8 | |
| SCHEMBL17068306 | 0.84 | — | — | |
| SCHEMBL14950779 | 0.84 | — | — | |
| SCHEMBL17068305 | 0.84 | — | — | |
| SCHEMBL18467421 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9561212-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-02-07 | — | — | US | disclosed |