Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914777 | 0.94 | POLB (0.37) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL16559843 | 0.93 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL19158940 | 0.93 | POLB (0.38) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL21087700 | 0.90 | POLB (0.33) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL18468447 | 0.89 | POLB (0.38) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL16559858 | 0.89 | POLB (0.43) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL16559855 | 0.89 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL27255246 | 0.89 | POLB (0.42) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL19157428 | 0.89 | POLB (0.42) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL19159115 | 0.88 | POLB (0.36) | POLBAPEX1HTTTDP1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306615-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2024-01-17 | — | — | EP | disclosed |
| EP-4209567-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2023-07-12 | — | — | EP | disclosed |
| EP-4209568-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2023-07-12 | — | — | EP | disclosed |
| EP-4209566-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2023-07-12 | — | — | EP | disclosed |