Nitric Acid

Nitric Acid

SCHEMBL1846972

NCCNCCN.O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5B Q9Y2D0 6/20 0.56
CA12 O43570 5/20 0.56
CA6 P23280 5/20 0.56
CA7 P43166 5/20 0.56
CA9 Q16790 5/20 0.56
CA14 Q9ULX7 5/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
RECQL P46063 2/20 0.56
CA5A P35218 5/20 0.53
CA2 P00918 4/20 0.53
CA4 P22748 4/20 0.53
ALOX15 P16050 4/20 0.53
LMNA P02545 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
CA3 P07451 3/20 0.53
CA1 P00915 2/20 0.53
ALDH1A1 P00352 1/20 0.53
TP53 P04637 1/20 0.53
KDM4E B2RXH2 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL8763088 1.00 CA5B (0.56) CA5BCA12CA6CA7CA9
Nitric Acid SCHEMBL2734480 1.00 CA5B (0.56) CA5BCA12CA6CA7CA9
Nitric Acid SCHEMBL19272424 1.00 CA5B (0.56) CA5BCA12CA6CA7CA9
Trientine SCHEMBL10626916 0.97 CA5B (0.58) CA5BCA12CA6CA7CA9
Nitric Acid SCHEMBL28326268 0.91 CA5B (0.46) CA5BCA12CA6CA7CA9
SCHEMBL9749634 0.86 CA12 (0.59) CA5BCA12CA6CA7CA9
SCHEMBL3910107 0.86 CA12 (0.59) CA5BCA12CA6CA7CA9
SCHEMBL9340665 0.86 CA12 (0.59) CA5BCA12CA6CA7CA9
SCHEMBL3910104 0.86 CA12 (0.59) CA5BCA12CA6CA7CA9
SCHEMBL3903636 0.86 CA12 (0.59) CA5BCA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210253492-A1 SYSTEMS FOR PRODUCING DEMN EUTECTIC NORTHROP GRUMMAN SYSTEMS CORPORATION 2021-08-19 US claimed
US-10836687-B2 Systems for producing DEMN eutectic, and related methods of forming an energetic composition Northrop Grumman Innovation Systems, Inc. (US) 2020-11-17 US claimed
US-20170233307-A1 SYSTEMS FOR PRODUCING DEMN EUTECTIC, AND RELATED METHODS OF FORMING AN ENERGETIC COMPOSITION NORTHROP GRUMMAN SYSTEMS CORPORATION 2017-08-17 US claimed
US-9650307-B2 Methods for producing DEMN eutectic ORBITAL ATK, INC. (US) 2017-05-16 US claimed
WO-2014158629-A1 METHODS AND SYSTEMS FOR PRODUCING DEMN EUTECTIC, AND RELATED METHODS OF PRODUCING ENERGETIC COMPOSITIONS ALLIANT TECHSYSTEMS INC. (US) 2014-10-02 WO claimed
US-20140261930-A1 METHODS AND SYSTEMS FOR PRODUCING DEMN EUTECTIC, AND RELATED METHODS OF PRODUCING ENERGETIC COMPOSITIONS ALLIANT TECHSYSTEMS INC. (US) 2014-09-18 US claimed
US-8663406-B1 Melt cast insensitive eutectic explosive THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2014-03-04 US claimed
US-4718954-A OXIDIZER, SENSITIZER, GEL THERMEX ENERGY CORPORATION (US) 1988-01-12 US claimed
US-4481048-A AMMONIUM NITRATE AND DIETHYLENETRIAMINE TRINITRATE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-11-06 US claimed
US-20210253492-A1 SYSTEMS FOR PRODUCING DEMN EUTECTIC NORTHROP GRUMMAN SYSTEMS CORPORATION 2021-08-19 US disclosed
US-20210253492-A1 SYSTEMS FOR PRODUCING DEMN EUTECTIC NORTHROP GRUMMAN SYSTEMS CORPORATION 2021-08-19 US disclosed
US-10836687-B2 Systems for producing DEMN eutectic, and related methods of forming an energetic composition Northrop Grumman Innovation Systems, Inc. (US) 2020-11-17 US disclosed
US-10836687-B2 Systems for producing DEMN eutectic, and related methods of forming an energetic composition Northrop Grumman Innovation Systems, Inc. (US) 2020-11-17 US disclosed
EP-2325155-B1 STABILIZED COMPOSITIONS COMPRISING AMMONIUM NITRATE ADVANSIX RESINS & CHEMICALS LLC (US) 2019-05-08 EP disclosed
EP-1981830-A2 STABILIZED COMPOSITIONS COMPRISING AMMONIUM NITRATE Honeywell International Inc. (US) 2008-10-22 EP disclosed
US-20070199357-A1 Compositions comprising ammonium nitrate double salts HONEYWELL INTERNATIONAL INC. (US) 2007-08-30 US disclosed
WO-2007084873-A2 STABILIZED COMPOSITIONS COMPRISING AMMONIUM NITRATE HONEYWELL INTERNATIONAL INC. (US) 2007-07-26 WO disclosed
US-4718954-A OXIDIZER, SENSITIZER, GEL THERMEX ENERGY CORPORATION (US) 1988-01-12 US disclosed
US-4481048-A AMMONIUM NITRATE AND DIETHYLENETRIAMINE TRINITRATE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-11-06 US disclosed
US-4481048-A AMMONIUM NITRATE AND DIETHYLENETRIAMINE TRINITRATE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-11-06 US disclosed