Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA6 | P23280 | 5/20 | 0.56 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CA3 | P07451 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL8763088 | 1.00 | CA5B (0.56) | CA5BCA12CA6CA7CA9 | |
| Nitric Acid SCHEMBL1846972 | 1.00 | CA5B (0.56) | CA5BCA12CA6CA7CA9 | |
| Nitric Acid SCHEMBL19272424 | 1.00 | CA5B (0.56) | CA5BCA12CA6CA7CA9 | |
| Trientine SCHEMBL10626916 | 0.97 | CA5B (0.58) | CA5BCA12CA6CA7CA9 | |
| Nitric Acid SCHEMBL28326268 | 0.91 | CA5B (0.46) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL9749634 | 0.86 | CA12 (0.59) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL3910107 | 0.86 | CA12 (0.59) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL9340665 | 0.86 | CA12 (0.59) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL3910104 | 0.86 | CA12 (0.59) | CA5BCA12CA6CA7CA9 | |
| SCHEMBL3903636 | 0.86 | CA12 (0.59) | CA5BCA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5485722-A | Catalytic decomposition of hydroxylammonium nitrate-based monopropellants | OLIN CORPORATION (US) | 1996-01-23 | — | — | US | claimed |
| EP-2158395-B1 | HYDROXY AMINE BASED STAGED COMBUSTION HYBRID ROCKET MOTOR | RAYTHEON CO (US) | 2018-06-20 | — | — | EP | disclosed |
| EP-2714264-B1 | CATALYST, GAS GENERATOR, AND THRUSTER WITH IMPROVED THERMAL CAPABILITY AND CORROSION RESISTANCE | AEROJET ROCKETDYNE INC (US) | 2018-05-02 | — | — | EP | disclosed |
| US-20120304620-A1 | CATALYST, GAS GENERATOR, AND THRUSTER WITH IMPROVED THERMAL CAPABILITY AND CORROSION RESISTANCE | AEROJET-GENERAL CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2012166335-A1 | CATALYST, GAS GENERATOR, AND THRUSTER WITH IMPROVED THERMAL CAPABILITY AND CORROSION RESISTANCE | AEROJET-GENERAL CORPORATION (US) | 2012-12-06 | — | — | WO | disclosed |
| US-7966805-B2 | Hydroxyl amine based staged combustion hybrid rocket motor | RAYTHEON COMPANY (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2158395-A1 | HYDROXY AMINE BASED STAGED COMBUSTION HYBRID ROCKET MOTOR | Raytheon Company (US) | 2010-03-03 | — | — | EP | disclosed |
| US-20090211227-A1 | Hydroxyl Amine Based Staged Combustion Hybrid Rocket Motor | RAYTHEON COMPANY | 2009-08-27 | — | — | US | disclosed |
| WO-2008144324-A1 | HYDROXY AMINE BASED STAGED COMBUSTION HYBRID ROCKET MOTOR | RAYTHEON COMPANY (US) | 2008-11-27 | — | — | WO | disclosed |
| US-5485722-A | Catalytic decomposition of hydroxylammonium nitrate-based monopropellants | OLIN CORPORATION (US) | 1996-01-23 | — | — | US | disclosed |