Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173316 | 0.86 | CYP11B1 (0.59) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL29006790 | 0.85 | CYP3A4 (0.58) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL1803160 | 0.83 | ESR2 (0.65) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL1491549 | 0.83 | CYP2A6 (0.64) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL5684882 | 0.81 | AXL (0.59) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL14493330 | 0.81 | CYP2A6 (0.54) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5687723 | 0.79 | AXL (0.58) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL30732664 | 0.79 | CYP2A6 (0.58) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL1155160 | 0.79 | ALDH1A1 (0.60) | NPC1RAB9AMAPTCYP11B1CYP3A4 | |
| SCHEMBL30070521 | 0.79 | ALDH1A1 (0.60) | NPC1RAB9AMAPTCYP11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323612-B1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | UNIGEN INC (US) | 2019-07-10 | — | — | EP | claimed |
| US-20160083322-A1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | UNIGEN, INC. (US) | 2016-03-24 | — | — | US | claimed |
| EP-2323612-A1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | Unigen, Inc. (US) | 2011-05-25 | — | — | EP | claimed |
| WO-2010011630-A1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-01-28 | — | — | WO | claimed |
| US-20100016347-A1 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-01-21 | — | — | US | claimed |
| US-12227472-B2 | Series of skin-whitening (lightening) compounds | UNIGEN, INC. (US) | 2025-02-18 | — | — | US | disclosed |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | UNIGEN, INC. (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | UNIGEN, INC. (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | UNIGEN, INC. (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230304932-A1 | COMPOSITIONS, SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS INVOLVING ENERGY TRANSFER DYE CONJUGATES AND ANALYTES COMPRISING THE SAME | Life Technologies Corporation | 2023-09-28 | — | — | US | disclosed |
| US-20230304932-A1 | COMPOSITIONS, SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS INVOLVING ENERGY TRANSFER DYE CONJUGATES AND ANALYTES COMPRISING THE SAME | Life Technologies Corporation | 2023-09-28 | — | — | US | disclosed |
| US-11739040-B2 | Series of skin-whitening (lightening) compounds | UNIGEN, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20100016347-A1 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20100016347-A1 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20100016347-A1 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-RE39663-E1 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes | APPLERA CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1196640-B1 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1196640-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | Applera Corporation (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001057264-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| US-6221604-B1 | CONJUGATED TO SUBSTRATES SUCH AS NUCLEOSIDES OR NUCLEOTIDES AND USED AS DETECTION LABELS IN MOLECULAR BIOLOGY EXPERIMENTS; ENERGY TRANSFER DYE | PE CORPORATION | 2001-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083322-A1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | TYR, TH, MAOB | NPC1 4496/4885RAB9A 3320/4885MAPT 372/4885 |
| US-11739040-B2 | Series of skin-whitening (lightening) compounds | TYR, TH, MAOB | NPC1 4496/4885RAB9A 3320/4885MAPT 372/4885 |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | TYR, TH, MAOB | NPC1 4496/4885RAB9A 3320/4885MAPT 372/4885 |
| US-20100016347-A1 | SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS | TYR, MAOB, TH | NPC1 4322/4885RAB9A 3563/4885MAPT 332/4885 |
| US-12227472-B2 | Series of skin-whitening (lightening) compounds | TYR, TH, MAOB | NPC1 4496/4885RAB9A 3320/4885MAPT 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.