SCHEMBL30732664

SCHEMBL30732664

Oc1cnccc1-c1cccnc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.58
CYP3A4 P08684 3/20 0.58
ALDH1A1 P00352 2/20 0.58
CYP1A2 P05177 2/20 0.58
KDM4E B2RXH2 2/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
GSK3B P49841 1/20 0.49
DYRK1A Q13627 1/20 0.49
CYP2E1 P05181 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
NUDT1 P36639 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7465016 0.87 RPS6KA3 (0.54) CYP2A6CYP3A4ALDH1A1CYP1A2HPGD
SCHEMBL23775013 0.83 CYP2A6 (0.58) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL29775933 0.83 CYP2A6 (0.58) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL30070521 0.83 ALDH1A1 (0.60) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL1155160 0.83 ALDH1A1 (0.60) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL1491549 0.82 CYP2A6 (0.64) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL22236422 0.81 RPS6KA3 (0.50) KDM4EERN1RPS6KA3
Hydrochloric Acid SCHEMBL21412299 0.81 ALDH1A1 (0.58) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL1847280 0.79 NPC1 (0.63) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL10205403 0.77 CYP19A1 (0.61) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 EP disclosed
WO-2023239906-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2023-12-14 WO disclosed