Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 9/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18384694 | 0.80 | MAPT (0.35) | LMNARECQLPDE4APDE4BPDE4C | |
| SCHEMBL18384682 | 0.78 | LMNA (0.43) | LMNARECQLPDE4APDE4BPDE4C | |
| SCHEMBL18391662 | 0.77 | CSNK2A2 (0.38) | LMNAALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL29488 | 0.77 | LMNA (0.50) | LMNARECQLPDE4APDE4BPDE4C | |
| SCHEMBL18384679 | 0.73 | TSHR (0.44) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL22545044 | 0.73 | ACHE (0.36) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL18384689 | 0.72 | LMNA (0.43) | LMNARECQLPDE4APDE4BPDE4C | |
| SCHEMBL18384647 | 0.70 | PDE4A (0.47) | LMNARECQLPDE4APDE4BPDE4C | |
| SCHEMBL18384660 | 0.70 | PDE4A (0.47) | LMNARECQLPDE4APDE4BPDE4C | |
| SCHEMBL10821119 | 0.70 | LMNA (0.52) | LMNARECQLPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3127907-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | Boston Biomedical, Inc. (US) | 2017-02-08 | — | — | EP | disclosed |