Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18474217 | 1.00 | DPP4 (0.45) | DPP4CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL27827757 | 0.91 | KMT2A (0.43) | DPP4CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL18849795 | 0.88 | ALDH1A1 (0.49) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL18474161 | 0.88 | ALDH1A1 (0.49) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL23746785 | 0.88 | ALDH1A1 (0.49) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL20253880 | 0.84 | TDP1 (0.45) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL25967749 | 0.83 | KMT2A (0.50) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL18474216 | 0.82 | CHRNA7 (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4POLB | |
| SCHEMBL27945266 | 0.82 | CHRNA7 (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4POLB | |
| SCHEMBL8787587 | 0.79 | SPHK1 (0.46) | DPP4SPHK1SPHK2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023894-A1 | MTHFD2 INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-02-09 | — | — | WO | disclosed |