Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 8/20 | 0.32 |
| ▸ | CA2 | P00918 | 8/20 | 0.32 |
| ▸ | CA9 | Q16790 | 7/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842441 | 1.00 | THRB (0.33) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL2785934 | 0.91 | ADRB2 (0.33) | TSHR | |
| SCHEMBL29566754 | 0.89 | HTT (0.46) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL477641 | 0.85 | ADRB2 (0.32) | — | |
| SCHEMBL333713 | 0.85 | — | — | |
| SCHEMBL19809187 | 0.84 | THRB (0.35) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL703902 | 0.84 | THRB (0.35) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL708500 | 0.84 | THRB (0.35) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL5575092 | 0.82 | TSHR (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL11332079 | 0.82 | TSHR (0.40) | THRBTSHRMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2712886-B1 | TIRE HAVING SYNTHETIC RUBBER BASED OUTER RUBBER SIDEWALL | GOODYEAR TIRE & RUBBER (US) | 2015-06-24 | — | — | EP | claimed |
| EP-1640182-B1 | Aircraft tire | GOODYEAR TIRE & RUBBER (US) | 2011-05-18 | — | — | EP | claimed |
| EP-1767571-B1 | Tire with tread containing tin coupled amine functionalized polybutadiene and nanostructured inversion carbon black | GOODYEAR TIRE & RUBBER (US) | 2008-11-19 | — | — | EP | claimed |
| EP-1726617-B1 | Tire with tread comprised of natural rubber and specialized emulsion prepared styrene/butadiene elastomer | GOODYEAR TIRE & RUBBER (US) | 2008-05-14 | — | — | EP | claimed |
| EP-1593528-B1 | Tire with tread of specialized trans 1,4-polybutadiene polymer and cis 1,4-polyisoprene natural rubber | GOODYEAR TIRE & RUBBER (US) | 2007-01-10 | — | — | EP | claimed |