Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218077 | 0.81 | TSHR (0.50) | ALDH1A1KMT2AGAAF10LMNA | |
| SCHEMBL611205 | 0.81 | TSHR (0.50) | ALDH1A1KMT2AGAAF10LMNA | |
| SCHEMBL5213193 | 0.81 | TSHR (0.50) | ALDH1A1KMT2AGAAF10LMNA | |
| SCHEMBL5338500 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL12722614 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL12722664 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL7397160 | 0.80 | ALDH1A1 (0.43) | ALDH1A1PREPMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL9084788 | 0.80 | TSHR (0.52) | ALDH1A1KMT2AGAAF10LMNA | |
| Hydrochloric Acid SCHEMBL6307871 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL22710505 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567304-B2 | Quinazolinedione derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2017-02-14 | — | — | US | disclosed |