Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367007 | 0.94 | ALDH1A1 (0.43) | ALDH1A1FKBP1AMEN1KMT2AGAA | |
| SCHEMBL8036361 | 0.88 | ITGB3 (0.45) | ALDH1A1FKBP1AMEN1KMT2AGAA | |
| SCHEMBL5213193 | 0.81 | TSHR (0.50) | ALDH1A1KMT2AGAAF10HTR2C | |
| SCHEMBL5218077 | 0.81 | TSHR (0.50) | ALDH1A1KMT2AGAAF10HTR2C | |
| SCHEMBL611205 | 0.81 | TSHR (0.50) | ALDH1A1KMT2AGAAF10HTR2C | |
| SCHEMBL18477759 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AGAAF10 | |
| SCHEMBL4031368 | 0.80 | PREP (0.41) | ALDH1A1FKBP1AMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL9084788 | 0.79 | TSHR (0.52) | ALDH1A1KMT2AGAAF10HTR2C | |
| SCHEMBL5225669 | 0.78 | MAPT (0.48) | HTR2CITGB3ITGA2B | |
| SCHEMBL10957606 | 0.77 | TSHR (0.49) | ALDH1A1FKBP1AGAAF10HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080069-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999054284-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |