Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719546 | 0.84 | SMN1; SMN2 (0.51) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL10723996 | 0.83 | PTGS1 (0.48) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL6632291 | 0.83 | CYP1A2 (0.54) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL11078345 | 0.83 | SMN1; SMN2 (0.47) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL28950163 | 0.83 | CYP1A2 (0.47) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL6270396 | 0.80 | SMN1; SMN2 (0.51) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL20509384 | 0.79 | SMN1; SMN2 (0.54) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL27957667 | 0.79 | CYP1A2 (0.43) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL11684240 | 0.79 | SMN1; SMN2 (0.56) | MAPTALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL10720726 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1GAASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321309-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2011-05-18 | — | — | EP | disclosed |
| WO-2009156966-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |