Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20509384 | 0.86 | SMN1; SMN2 (0.54) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL11684240 | 0.86 | SMN1; SMN2 (0.56) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL10720726 | 0.86 | SMN1; SMN2 (0.56) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL8795716 | 0.84 | SMN1; SMN2 (0.55) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL21629502 | 0.84 | SMN1; SMN2 (0.55) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL8795722 | 0.84 | SMN1; SMN2 (0.59) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL11717998 | 0.83 | SMN1; SMN2 (0.48) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL10535907 | 0.83 | SMN1; SMN2 (0.54) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL1847840 | 0.83 | MAPT (0.53) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL5131881 | 0.83 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP3A4CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105295197-B | Method for regulating and controlling crystal form in iPP-EPDM rubber-plastic blended material by adopting double constant-temperature heating tables | 安徽大学 | 2017-06-13 | — | — | CN | claimed |
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |