SCHEMBL1847846

SCHEMBL1847846

CO[Si](C=C(C)C(=O)O)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 3/20 0.33
PTGS1 P23219 1/20 0.32
AKR1C3 P42330 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4193938 1.00 APEX1 (0.33) APEX1PTGS1AKR1C3ALDH1A1
SCHEMBL28283714 0.98 APEX1 (0.32) APEX1PTGS1AKR1C3
Hydrogen Sulfide SCHEMBL29015863 0.98 APEX1 (0.32) APEX1PTGS1AKR1C3
SCHEMBL28004129 0.78 APEX1 (0.32) APEX1PTGS1AKR1C3
SCHEMBL28796433 0.77 TSHR (0.45) APEX1ALDH1A1
SCHEMBL4918084 0.76 PTGS1 (0.30) PTGS1AKR1C3
SCHEMBL29376854 0.75 TSHR (0.32)
SCHEMBL9000926 0.75 ALDH1A1 (0.37) ALDH1A1
Hydrogen Sulfide SCHEMBL28347908 0.73 ALDH1A1 (0.36) ALDH1A1
SCHEMBL16243794 0.72 AKR1C3 (0.31) APEX1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112826976-A Preparation of low-whitening cyanoacrylate medical adhesive 江西博恩锐尔生物科技有限公司 2021-05-25 CN claimed
US-20210077668-A1 Highly Adherent Polymers for Orthopedic Device Coatings MUSC FOUNDATION FOR RESEARCH DEVELOPMENT 2021-03-18 US claimed
CN-111001191-A Preparation method of environment-friendly pH response type oil-water separation material 西安科技大学 2020-04-14 CN claimed
CN-107262077-B A kind of preparation method being bonded organic polymer overmold silicon ball chromatographic stationary phases 华东理工大学 2019-11-15 CN claimed
CN-110082333-A A kind of preparation method of Cucurbituril [7] Studies of Fluorescent Film Sensors 山西中医药大学 2019-08-02 CN claimed
WO-2019136247-A1 HIGHLY ADHERENT POLYMERS FOR ORTHOPEDIC DEVICE COATINGS CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) 2019-07-11 WO claimed
CN-109485780-A Acryl plates and its preparation process 张金娥 2019-03-19 CN claimed
CN-109485779-A A kind of high-strength water-resistance acryl plates 张金娥 2019-03-19 CN claimed
CN-109295733-A A kind of preparation method of aqueous floride-free super-hydrophobic fabric 河北工业大学 2019-02-01 CN claimed
CN-108482755-A A kind of foods package closing machine 徐州工程学院 2018-09-04 CN claimed
CN-108102046-A A kind of organosilicon encapsulating material of secondary curing and preparation method thereof 华南师范大学 2018-06-01 CN claimed
CN-107262077-A A kind of preparation method for being bonded organic polymer overmold silicon ball chromatographic stationary phases 华东理工大学 2017-10-20 CN claimed
CN-102858821-B Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2015-04-22 CN claimed
CN-102115515-A Copolymer for improving wettability of silicone hydrogel, silicone hydrogel composition containing same and ophthalmic article prepared therefrom FAR EASTERN NEW CENTURY CORP 2011-07-06 CN claimed
CN-114459877-B DNA tetrahedron composite magnetic nano material for enriching exosomes and preparation thereof 中国计量科学研究院 2024-05-10 CN disclosed
US-20240034853-A1 BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE Renovo Concepts, Inc. 2024-02-01 US disclosed
CN-115584033-B Dispersing agent for pulping low-rank coal and preparation method thereof 山西远航建材有限公司 2024-01-30 CN disclosed
US-5679722-A A LIQUID PHOTOCURABLE RESIN, A REINFORCING AGENT SELECTED FROM INORGANIC SOLID PARTICLES OR WHISKERS HAVING SPECIFIC PARTICLE DIAMETER TEIJIN SEIKI CO., LTD. (JP) 1997-10-21 US disclosed
EP-0781639-A2 A mold of a photocured resin containing a reinforcing agent Teijin Seiki Co., Ltd. (JP) 1997-07-02 EP disclosed
CN-1110978-A Resinated pigmnt compositions CIBA GEIGY AG (CH) 1995-11-01 CN disclosed