Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22354610 | 1.00 | ALDH1A1 (0.35) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL18478770 | 0.84 | PDK1 (0.32) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL18452324 | 0.81 | PDK1 (0.32) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL20465450 | 0.81 | PDK1 (0.32) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL8752895 | 0.78 | PDK1 (0.38) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL14915676 | 0.78 | PDK1 (0.38) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL22354601 | 0.78 | CHRNA1 (0.30) | — | |
| SCHEMBL7083033 | 0.78 | MAPT (0.36) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL17020348 | 0.78 | MEN1 (0.38) | ALDH1A1PDK1PPM1BPTPN1PPP1CC | |
| SCHEMBL7625468 | 0.78 | MEN1 (0.38) | ALDH1A1PDK1PPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2017023774-A9 | PRODRUGS OF GLUTAMINE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017023774-A1 | PRODRUGS OF GLUTAMINE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-02-09 | — | — | WO | disclosed |