Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | XBP1 | P17861 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389539 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL24476658 | 0.83 | MAPK1 (0.69) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL18479755 | 0.83 | KDM4E (0.76) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL18441020 | 0.82 | HPGD (0.82) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL19066312 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL31068491 | 0.79 | MAPK1 (0.63) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL27628883 | 0.79 | KDM4E (0.78) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL18479758 | 0.77 | TSHR (0.64) | ALDH1A1MAPK1HSD17B10TSHRHTT | |
| SCHEMBL5075030 | 0.76 | MEN1 (0.81) | ALDH1A1MAPK1TSHRHTTSMN1; SMN2 | |
| SCHEMBL5075995 | 0.75 | MEN1 (0.83) | ALDH1A1MAPK1HPGDTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017021435-A1 | ANTAGONISTS OF THE GOLGI REASSEMBLY-STACKING PROTEIN OF 55 KDA (GRASP55) AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-02-09 | — | — | WO | disclosed |