Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318850 | 0.79 | SLC7A5 (0.47) | DAOPOLBKMT2ATDP1THRB | |
| SCHEMBL8306982 | 0.79 | SLC7A5 (0.47) | DAOPOLBKMT2ATDP1THRB | |
| SCHEMBL2921395 | 0.74 | PRSS1 (0.47) | DAOPOLBKMT2ATDP1PRMT6 | |
| SCHEMBL1520622 | 0.72 | ALOX5 (0.46) | DAOPOLBKMT2ATDP1TP53 | |
| SCHEMBL5262305 | 0.72 | PRMT6 (0.47) | PRMT6TP53THRB | |
| SCHEMBL1260565 | 0.72 | KMT2A (0.50) | DAOPOLBKMT2ATDP1PRMT6 | |
| SCHEMBL6636274 | 0.72 | PRMT6 (0.47) | PRMT6TP53THRB | |
| SCHEMBL2027702 | 0.71 | CYP2C19 (0.61) | DAOPOLBTDP1HPGDDPP4 | |
| SCHEMBL975049 | 0.71 | DPP4 (0.56) | KMT2AS1PR2S1PR1ALDH1A1HPGD | |
| SCHEMBL2027703 | 0.71 | CYP2C19 (0.61) | DAOPOLBTDP1HPGDDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320738-A1 | SUBSTITUTED AMINOTHIAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE | TransTech Pharma, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |