Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801388 | 0.77 | PRMT6 (0.48) | KMT2AALDH1A1KDM4EMEN1GAA | |
| SCHEMBL9917335 | 0.74 | PRMT6 (0.50) | KMT2AALDH1A1KDM4EMEN1GAA | |
| SCHEMBL6533651 | 0.71 | BLM (0.50) | BLMKMT2AALDH1A1POLBTDP1 | |
| SCHEMBL1260565 | 0.71 | KMT2A (0.50) | BLMKMT2AALDH1A1POLBTDP1 | |
| SCHEMBL14547348 | 0.70 | BLM (0.73) | BLMKMT2AALDH1A1POLBTDP1 | |
| SCHEMBL15218062 | 0.70 | BLM (0.73) | BLMKMT2AALDH1A1POLBTDP1 | |
| SCHEMBL19169552 | 0.70 | RIPK1 (0.47) | KMT2AALDH1A1POLBTDP1KDM4E | |
| SCHEMBL122295 | 0.69 | BLM (0.72) | BLMKMT2AALDH1A1POLBTDP1 | |
| SCHEMBL122296 | 0.69 | BLM (0.72) | BLMKMT2AALDH1A1POLBTDP1 | |
| SCHEMBL19176979 | 0.69 | RIPK1 (0.46) | KMT2AALDH1A1KDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320738-A1 | SUBSTITUTED AMINOTHIAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE | TransTech Pharma, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |