Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17571469 | 0.81 | KDM4E (0.56) | LTA4HMEN1LMNAHTTKMT2A | |
| SCHEMBL18474438 | 0.81 | LTA4H (0.55) | LTA4HMEN1LMNAHTTKMT2A | |
| SCHEMBL17555438 | 0.81 | LTA4H (0.55) | LTA4HPTGS2MEN1LMNAHTT | |
| SCHEMBL30063493 | 0.81 | LTA4H (0.58) | LTA4HPTGS1PTGS2MEN1LMNA | |
| SCHEMBL545871 | 0.81 | LTA4H (0.58) | LTA4HPTGS1PTGS2MEN1LMNA | |
| SCHEMBL18474533 | 0.79 | KDM4E (0.63) | LTA4HMEN1LMNAHTTKMT2A | |
| SCHEMBL17562439 | 0.78 | KDM4E (0.63) | LTA4HPTGS1PTGS2MEN1LMNA | |
| SCHEMBL17556315 | 0.76 | LTA4H (0.51) | LTA4HPTGS1PTGS2HRH3KDM4E | |
| SCHEMBL17555511 | 0.76 | LTA4H (0.44) | LTA4HPTGS1PTGS2HRH3BACE1 | |
| SCHEMBL18483417 | 0.76 | LTA4H (0.66) | LTA4HLMNAHTTMCHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024021-A1 | 3-(1H-PYRROLO[2,3-B]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2017-02-09 | — | — | WO | disclosed |