Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686849 | 0.79 | CYP1A2 (0.64) | CYP1A2CYP1A1CYP1B1ACHECA9 | |
| SCHEMBL5294640 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP1A1CYP1B1ACHEALDH1A1 | |
| SCHEMBL14655673 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP1A1CYP1B1ACHEMEN1 | |
| SCHEMBL14394423 | 0.78 | ABL1 (0.47) | CYP1A2CYP1A1CYP1B1CA9ALDH1A1 | |
| SCHEMBL2093561 | 0.73 | ALDH1A1 (0.48) | CYP1A2CYP1A1CYP1B1CA9ALDH1A1 | |
| Formaldehyde SCHEMBL28179692 | 0.73 | CYP1A2 (0.57) | CYP1A2CYP1A1CYP1B1ACHECA9 | |
| SCHEMBL1547457 | 0.72 | ALDH1A1 (0.61) | CYP1A2CYP1A1CYP1B1CA9ALDH1A1 | |
| SCHEMBL1576523 | 0.72 | GAA (0.59) | CA9ALDH1A1MAPTCA12CA1 | |
| SCHEMBL5236856 | 0.71 | TUBB1 (0.58) | CYP1A2CYP1A1CYP1B1ACHECA9 | |
| SCHEMBL684136 | 0.71 | ACHE (0.52) | CYP1A2CYP1A1CYP1B1ACHECA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024319-A1 | TUNABLE ENDOGENOUS PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-09 | — | — | WO | disclosed |