Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.34 |
| ▸ | SLC34A3 | Q8N130 | 1/20 | 0.34 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 7/20 | 0.33 |
| ▸ | BRAF | P15056 | 5/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18482711 | 0.91 | SLC34A2 (0.56) | SLC34A2NPSR1L3MBTL1KDM4ESLC34A1 | |
| SCHEMBL19595651 | 0.90 | SLC34A2 (0.48) | SLC34A2NPSR1KDM4ERAF1BRAF | |
| SCHEMBL45407 | 0.89 | SLC34A2 (0.63) | SLC34A2NPSR1L3MBTL1KDM4EDDR1 | |
| SCHEMBL46451 | 0.82 | SLC34A2 (0.63) | SLC34A2NPSR1DDR1MEN1CYP1A2 | |
| SCHEMBL40143 | 0.81 | SLC34A2 (0.61) | SLC34A2KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL15444399 | 0.81 | SLC34A2 (0.45) | SLC34A2L3MBTL1RAF1BRAFALDH1A1 | |
| SCHEMBL40087 | 0.81 | SLC34A2 (0.61) | SLC34A2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL39846 | 0.81 | SLC34A2 (0.63) | SLC34A2DDR1MEN1CYP1A2CYP2C19 | |
| SCHEMBL46383 | 0.80 | SLC34A2 (0.70) | SLC34A2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL39971 | 0.80 | SLC34A2 (0.59) | SLC34A2NPSR1KDM4ERAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-20170037010-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037010-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A2, SLC34A1, SLC10A2 | SLC34A2 1/4885NPSR1 818/4885L3MBTL1 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.