Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | GJB2 | P29033 | 1/20 | 0.44 |
| ▸ | TACR2 | P21452 | 3/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400344 | 0.92 | HTR1A (0.51) | PDE4DHTR1ANT5EGJB2TACR2 | |
| SCHEMBL10352583 | 0.92 | HTR1A (0.51) | PDE4DHTR1ANT5EGJB2TACR2 | |
| SCHEMBL21657197 | 0.91 | HTR1A (0.50) | PDE4DHTR1ANT5ETACR2SSTR4 | |
| SCHEMBL21013403 | 0.89 | SLC6A2 (0.53) | PDE4DSLC6A2HTR1ANT5EGJB2 | |
| SCHEMBL21013113 | 0.85 | GJB2 (0.54) | SLC6A2HTR1ANT5EGJB2TACR2 | |
| SCHEMBL18483252 | 0.85 | HTR1A (0.42) | PDE4DSLC6A2HTR1ANT5EGJB2 | |
| SCHEMBL22710060 | 0.85 | GJB2 (0.46) | PDE4DSLC6A2HTR1ANT5EGJB2 | |
| SCHEMBL7151150 | 0.85 | GJB2 (0.46) | PDE4DSLC6A2HTR1ANT5EGJB2 | |
| SCHEMBL18929913 | 0.85 | GJB2 (0.46) | PDE4DSLC6A2HTR1ANT5EGJB2 | |
| SCHEMBL17626958 | 0.85 | GJB2 (0.46) | PDE4DSLC6A2HTR1ANT5EGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331893-B1 | MANNOSE DERIVATIVES USEFUL FOR TREATING PATHOLOGIES ASSOCIATED WITH ADHERENT E. COLI | ENTEROME (FR) | 2019-05-22 | — | — | EP | disclosed |
| WO-2017021549-A1 | MANNOSE DERIVATIVES USEFUL FOR TREATING PATHOLOGIES ASSOCIATED WITH ADHERENT E. COLI | ENTEROME (FR) | 2017-02-09 | — | — | WO | disclosed |