Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483213 | 0.89 | ALDH1A1 (0.41) | MAPTTHRBALDH1A1HPGDKMT2A | |
| SCHEMBL19205620 | 0.89 | ALDH1A1 (0.41) | MAPTTHRBALDH1A1HPGDKMT2A | |
| SCHEMBL19205805 | 0.88 | TAAR1 (0.39) | MAPTTHRBALDH1A1KMT2AMEN1 | |
| SCHEMBL19205804 | 0.88 | TAAR1 (0.39) | MAPTTHRBALDH1A1KMT2AMEN1 | |
| SCHEMBL18484101 | 0.86 | KMT2A (0.44) | MAPTTHRBALDH1A1HPGDKMT2A | |
| SCHEMBL18484100 | 0.86 | KMT2A (0.44) | MAPTTHRBALDH1A1HPGDKMT2A | |
| SCHEMBL18485915 | 0.83 | PIK3CD (0.36) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL19205745 | 0.81 | MAPT (0.41) | MAPTTHRBALDH1A1HPGDKMT2A | |
| SCHEMBL19205746 | 0.81 | MAPT (0.41) | MAPTTHRBALDH1A1HPGDKMT2A | |
| SCHEMBL19205688 | 0.79 | MMP2 (0.36) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017021879-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-02-09 | — | — | WO | disclosed |