Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | USP14 | P54578 | 2/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21227866 | 0.83 | NOTUM (0.56) | NOTUMKDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL2760337 | 0.79 | POLB (0.60) | NOTUMKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5857932 | 0.78 | ALDH1A1 (0.58) | NOTUMKDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL18482772 | 0.77 | NOTUM (0.53) | NOTUMKDM4ETSHRMAPK1SMN1; SMN2 | |
| SCHEMBL5329984 | 0.76 | PTGS2 (0.49) | NOTUMKDM4E | |
| SCHEMBL21225466 | 0.76 | ALDH1A1 (0.61) | NOTUMKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL21225484 | 0.75 | MAPT (0.54) | NOTUMKDM4ETSHRMAPK1SMN1; SMN2 | |
| SCHEMBL23245297 | 0.75 | KDM4E (0.50) | NOTUMKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21387140 | 0.74 | NOTUM (0.77) | NOTUMKDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1979515 | 0.74 | NOTUM (1.00) | NOTUMKDM4ESMN1; SMN2ALDH1A1USP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331893-B1 | MANNOSE DERIVATIVES USEFUL FOR TREATING PATHOLOGIES ASSOCIATED WITH ADHERENT E. COLI | ENTEROME (FR) | 2019-05-22 | — | — | EP | disclosed |
| WO-2017021549-A1 | MANNOSE DERIVATIVES USEFUL FOR TREATING PATHOLOGIES ASSOCIATED WITH ADHERENT E. COLI | ENTEROME (FR) | 2017-02-09 | — | — | WO | disclosed |