Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24462741 | 0.73 | HCRTR2 (0.39) | HCRTR2 | |
| SCHEMBL20021699 | 0.73 | HCRTR2 (0.39) | HCRTR2 | |
| SCHEMBL18483615 | 0.72 | HCRTR2 (0.33) | HCRTR2 | |
| SCHEMBL18507245 | 0.71 | HCRTR2 (0.31) | HCRTR2 | |
| SCHEMBL23194412 | 0.70 | HCRTR2 (0.35) | HCRTR2 | |
| SCHEMBL4762344 | 0.68 | HCRTR2 (0.38) | HCRTR2 | |
| SCHEMBL11991405 | 0.68 | HCRTR2 (0.38) | HCRTR2 | |
| SCHEMBL20334913 | 0.68 | MEN1 (0.36) | — | |
| SCHEMBL10327132 | 0.67 | HCRTR2 (0.41) | HCRTR2 | |
| SCHEMBL9066827 | 0.67 | HCRTR2 (0.39) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037032-A1 | AMINO PYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NOVARTIS AG (CH) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037032-A1 | AMINO PYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PI4KA, PIP4K2B, PHKG1 | HCRTR2 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.