Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18484135 | 1.00 | ACHE (0.35) | ACHEALOX5PDE3BPDE3ALMNA | |
| SCHEMBL19205748 | 0.88 | CYP2C9 (0.38) | PDE3BPDE3ATSHRL3MBTL1FYN | |
| SCHEMBL19205747 | 0.88 | CYP2C9 (0.38) | PDE3BPDE3ATSHRL3MBTL1FYN | |
| SCHEMBL19205814 | 0.88 | EGFR (0.40) | ALOX5PDE3BPDE3AKDM4ECSF1R | |
| SCHEMBL19205656 | 0.88 | EGFR (0.40) | ALOX5PDE3BPDE3AKDM4ECSF1R | |
| SCHEMBL19205658 | 0.88 | EGFR (0.40) | ALOX5PDE3BPDE3AKDM4ECSF1R | |
| SCHEMBL18448354 | 0.75 | ACHE (0.56) | ACHEPDE3BPDE3ALMNAMAPT | |
| SCHEMBL18483503 | 0.74 | CHRNA7 (0.36) | ALOX5CHRNA7 | |
| SCHEMBL18483502 | 0.74 | CHRNA7 (0.36) | ALOX5CHRNA7 | |
| SCHEMBL18484149 | 0.71 | EGFR (0.45) | ACHESMN1; SMN2KDM4EEGFRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017021879-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-02-09 | — | — | WO | disclosed |