Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483503 | 1.00 | CHRNA7 (0.36) | CHRNA7ALOX5PDE2AS1PR1CYP19A1 | |
| SCHEMBL19205711 | 0.89 | CHRM2 (0.38) | PDE2ACYP19A1 | |
| SCHEMBL19205713 | 0.89 | CHRM2 (0.38) | PDE2ACYP19A1 | |
| SCHEMBL19205640 | 0.85 | NUDT1 (0.38) | ALOX5 | |
| SCHEMBL19205639 | 0.85 | NUDT1 (0.38) | ALOX5 | |
| SCHEMBL19205659 | 0.85 | NUDT1 (0.38) | ALOX5 | |
| SCHEMBL18484135 | 0.74 | ACHE (0.35) | CHRNA7ALOX5 | |
| SCHEMBL18484133 | 0.74 | ACHE (0.35) | CHRNA7ALOX5 | |
| SCHEMBL17830830 | 0.69 | S1PR1 (0.44) | CHRNA7ALOX5S1PR1 | |
| SCHEMBL11568168 | 0.68 | CHRNA7 (0.39) | CHRNA7ALOX5CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017021879-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-02-09 | — | — | WO | disclosed |