Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24775105 | 0.79 | ALDH1A1 (0.38) | TSHRCHRM2ADRA1ARGS12GLA | |
| SCHEMBL13066991 | 0.76 | TDP1 (0.41) | TSHRCHRM2ADRA1ARGS12GLA | |
| SCHEMBL14979110 | 0.76 | CYP3A4 (0.43) | TSHRCHRM2ADRA1ARGS12GLA | |
| SCHEMBL15004145 | 0.76 | ADRA2C (0.39) | TSHRCHRM2ADRA1ARGS12GLA | |
| SCHEMBL12337184 | 0.72 | TDP1 (0.38) | TSHRCYP3A4PKMALOX15CYP2C19 | |
| SCHEMBL7550545 | 0.72 | KDM1A (0.41) | TSHRCHRM2ADRA1ARGS12GLA | |
| SCHEMBL12728404 | 0.72 | TDP1 (0.38) | TSHRCHRM2ADRA1ARGS12GLA | |
| SCHEMBL1637837 | 0.71 | AKR1C1 (0.45) | TSHRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1637843 | 0.71 | AKR1C1 (0.45) | TSHRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12963614 | 0.69 | TDP1 (0.45) | TSHRCYP3A4ALOX15HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323974-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | Ube Industries, Ltd. (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010022001-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | IM&T RESEARCH, INC. (US) | 2010-02-25 | — | — | WO | disclosed |