SCHEMBL18485463

SCHEMBL18485463

O=C(Oc1ccccc1)N1C(=O)c2ccc3ccccc3c2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.43
BCHE P06276 3/20 0.41
WDR5 P61964 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
NSD2 O96028 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
HKDC1 Q2TB90 1/20 0.38
SOS1 Q07889 1/20 0.38
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
SLC6A3 Q01959 1/20 0.36
CHRNA7 P36544 1/20 0.36
HTR3A P46098 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18485437 0.83 MAPT (0.43) DNMT1BCHEWDR5SMN1; SMN2MEN1
SCHEMBL18485415 0.81 KDM4E (0.45) BCHEMEN1ALDH1A1KMT2AMAPT
SCHEMBL8989777 0.80 BCHE (0.54) BCHESMN1; SMN2ALDH1A1KMT2AMAPT
SCHEMBL18485422 0.78 DNMT1 (0.46) DNMT1BCHEWDR5SMN1; SMN2MEN1
SCHEMBL18485464 0.78 KDM4E (0.51) BCHESMN1; SMN2MEN1ALDH1A1KMT2A
SCHEMBL18485438 0.78 DNMT1 (0.45) DNMT1WDR5SMN1; SMN2MEN1ALDH1A1
SCHEMBL18485428 0.77 ALDH1A1 (0.43) DNMT1BCHESMN1; SMN2MEN1ALDH1A1
SCHEMBL18485457 0.76 NPSR1 (0.44) DNMT1WDR5MEN1ALDH1A1KMT2A
SCHEMBL18485398 0.74 CES1 (0.47) DNMT1WDR5SMN1; SMN2MEN1ALDH1A1
SCHEMBL18485424 0.74 DNMT1 (0.41) DNMT1BCHEWDR5SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170117588-A1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2017-04-27 US disclosed
EP-3131153-A1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE Sumitomo Seika Chemicals Co., Ltd. (JP) 2017-02-15 EP disclosed