SCHEMBL18485437

SCHEMBL18485437

COC(=O)N1C(=O)c2ccc3ccccc3c2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 2/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
DNMT1 P26358 1/20 0.41
P2RX4 Q99571 2/20 0.40
WDR5 P61964 1/20 0.39
BCHE P06276 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
NSD2 O96028 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
STAT3 P40763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18485415 0.86 KDM4E (0.45) MAPTMEN1KMT2AALDH1A1BCHE
SCHEMBL18485438 0.83 DNMT1 (0.45) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL18485463 0.83 DNMT1 (0.43) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL18485428 0.82 ALDH1A1 (0.43) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL18485398 0.79 CES1 (0.47) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL18485424 0.79 DNMT1 (0.41) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL18485457 0.79 NPSR1 (0.44) MAPTMEN1KMT2AALDH1A1DNMT1
SCHEMBL18485446 0.78 P2RX4 (0.39) MAPTMEN1KMT2AALDH1A1P2RX4
SCHEMBL18485380 0.78 CES1 (0.50) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL4186290 0.78 DNMT1 (0.42) MAPTMEN1KMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170117588-A1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2017-04-27 US disclosed
EP-3131153-A1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE Sumitomo Seika Chemicals Co., Ltd. (JP) 2017-02-15 EP disclosed