Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847140 | 1.00 | TLR2 (0.50) | TLR2EPHX2CSNK1ECNR2CERT1 | |
| SCHEMBL1846613 | 1.00 | TLR2 (0.50) | TLR2EPHX2CSNK1ECNR2CERT1 | |
| SCHEMBL1846848 | 0.98 | TLR2 (0.48) | TLR2EPHX2CSNK1ECNR2TLR8 | |
| SCHEMBL1848754 | 0.94 | TLR8 (0.46) | TLR2EPHX2CNR2TLR8TLR7 | |
| SCHEMBL23634016 | 0.90 | TLR2 (0.51) | TLR2EPHX2CSNK1ECNR2FAAH | |
| SCHEMBL19087037 | 0.90 | TLR2 (0.51) | TLR2EPHX2CSNK1ECNR2FAAH | |
| SCHEMBL1091520 | 0.90 | TLR2 (0.51) | TLR2EPHX2CSNK1ECNR2FAAH | |
| SCHEMBL11349595 | 0.90 | TLR2 (0.51) | TLR2EPHX2CSNK1ECNR2FAAH | |
| SCHEMBL22363311 | 0.90 | TLR2 (0.51) | TLR2EPHX2CSNK1ECNR2FAAH | |
| SCHEMBL7065867 | 0.90 | TLR2 (0.51) | TLR2EPHX2CSNK1ECNR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186812-A | Methods for preparing fluoroalkyl arylsulfinyl compounds and fluorinated compounds thereto | UBE INDUSTRIES | 2011-09-14 | — | — | CN | disclosed |
| US-20110190511-A1 | Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto | IM&T RESEARCH, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| EP-2323974-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | Ube Industries, Ltd. (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20100152463-A1 | Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto | IM&T RESEARCH, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2010022001-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | IM&T RESEARCH, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152463-A1 | Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto | PFAS, AGPS, FDPS | TLR2 4825/4885EPHX2 333/4885CSNK1E 4256/4885 |
| US-20110190511-A1 | Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto | PFAS, AGPS, FDPS | TLR2 4782/4885EPHX2 637/4885CSNK1E 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.