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SCHEMBL18486274

SCHEMBL18486274

COc1ccc(C(OC[C@H]2O[C@@H](n3c(-c4ccc([N+](=O)[O-])cc4)nc4c(C=Cc5ccccc5)ncnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19689082 1.00 TYMP (0.30) TYMP
SCHEMBL18486397 0.87 SLC28A2 (0.34) TYMP
SCHEMBL19689094 0.87 SLC28A2 (0.34) TYMP
SCHEMBL18486265 0.86 TYMP (0.39) TYMP
SCHEMBL19689071 0.86 TYMP (0.39) TYMP
SCHEMBL17363634 0.81 TYMP (0.38) TYMP
SCHEMBL17363637 0.81 TYMP (0.38) TYMP
SCHEMBL16871857 0.79 TYMP (0.33) TYMP
SCHEMBL16871856 0.79 TYMP (0.39) TYMP
SCHEMBL18486341 0.78 TYMP (0.38) TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3130597-B1 OLIGONUCLEOTIDE HAVING A NON-NATURAL NUCLEOTIDE AT THE 5'-TERMINAL KYOWA KIRIN CO LTD (JP) 2021-11-10 — — EP disclosed
EP-3130597-A1 OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF Kyowa Hakko Kirin Co., Ltd. (JP) 2017-02-15 — — EP disclosed