Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848674 | 1.00 | TSHR (0.36) | TSHRNPSR1EPHX1TAS1R3TAS1R1 | |
| SCHEMBL17291825 | 0.84 | HTR1A (0.39) | NPSR1HTR1AALDH1A1KMT2A | |
| SCHEMBL19381478 | 0.78 | ALDH1A1 (0.47) | TSHRNPSR1EPHX1TAS1R3TAS1R1 | |
| SCHEMBL6397302 | 0.75 | ALDH1A1 (0.37) | HTR1AALDH1A1KMT2A | |
| SCHEMBL6390289 | 0.75 | ANPEP (0.42) | HTR1AALDH1A1KMT2A | |
| SCHEMBL6396632 | 0.75 | ALDH1A1 (0.37) | HTR1AALDH1A1KMT2A | |
| SCHEMBL6397294 | 0.75 | ALDH1A1 (0.37) | HTR1AALDH1A1KMT2A | |
| SCHEMBL6390292 | 0.75 | ANPEP (0.42) | HTR1AALDH1A1KMT2A | |
| SCHEMBL21316453 | 0.75 | ANPEP (0.42) | HTR1AALDH1A1KMT2A | |
| SCHEMBL1760526 | 0.75 | TSHR (0.44) | TSHRNPSR1EPHX1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283495-B2 | Process for preparing optically active cyclic amines | BAYER CROPSCIENCE GMBH (DE) | 2012-10-09 | — | — | US | disclosed |
| EP-1833781-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLIC AMINES | BAYER CROPSCIENCE AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| EP-1833781-A1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLIC AMINES | Bayer CropScience AG (DE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006072374-A1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLIC AMINES | BAYER CROPSCIENCE AG (DE) | 2006-07-13 | — | — | WO | disclosed |
| US-20060149080-A1 | Process for preparing optically active cyclic amines | BAYER CROPSCIENCE GMBH | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149080-A1 | Process for preparing optically active cyclic amines | H1-0, CHRM1, PRMT1 | TSHR 229/4885NPSR1 661/4885EPHX1 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.