Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768388 | 0.98 | P2RY14 (0.35) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL8767914 | 0.89 | P2RY14 (0.33) | P2RY14ESR2 | |
| SCHEMBL8767510 | 0.85 | GRM5 (0.41) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL2741543 | 0.84 | ESR2 (0.50) | CYP3A4CYP2C9P2RY14ESR2 | |
| SCHEMBL23510979 | 0.83 | CYP3A4 (0.34) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL25919448 | 0.81 | CYP3A4 (0.34) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL26373090 | 0.81 | CYP3A4 (0.32) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL17851229 | 0.80 | ESR2 (0.37) | CYP3A4CYP2C9MAPTKMT2AP2RY14 | |
| SCHEMBL18857284 | 0.78 | PAX8 (0.40) | CYP3A4CYP2C9APPHSP90AA1GAA | |
| SCHEMBL6462913 | 0.78 | CYP2C9 (0.47) | CYP3A4CYP2C9MAPTKMT2AP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230313044-A1 | COMPOUND, COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND DEVICE | DIC CORPORATION (JP) | 2023-10-05 | — | — | US | disclosed |
| US-11008514-B2 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2021-05-18 | — | — | US | disclosed |
| US-20210009901-A1 | Liquid-Crystal Display Devices Containing Polymerisable Compounds | MERCK PATENT GMBH (DE) | 2021-01-14 | — | — | US | disclosed |
| US-10738240-B2 | Thiadiazoloquinoxaline derivatives | MERCK PATENT GMBH (DE) | 2020-08-11 | — | — | US | disclosed |
| US-10273409-B2 | Liquid crystal displays and liquid crystalline media with homeotropic alignment | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2019-04-30 | — | — | US | disclosed |
| US-20180223187-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180179446-A1 | LIQUID CRYSTAL MEDIUM CONTAINING POLYMERISABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
| US-20180142153-A1 | THIADIAZOLOQUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180100104-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-20180022997-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20170037315-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230313044-A1 | COMPOUND, COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND DEVICE | NLK, TTI2, LBR | CYP3A4 4490/4885CYP2C9 4004/4885APP 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.